Anne-Laure Perraud, PhD

Anne-Laure Perraud
Associate Professor
Department of Biomedical Research
Anne-Laure Perraud, PhD, is a researcher at National Jewish Health. Dr. Perraud is in the Department of Biomedical Research.

Special Interests

Research Interests

Ion homeostasis regulation in immune cells.


Kansai Medical University (Osaka, Japan), Dept. of Molecular Genetics, Guest scientist in Prof. Tomohiro Kurosaki''s research
University of Würzburg, Germany, PhD
University of Marburg, Germany, MS (Diplom)
University of Bonn, Germany, BA (Vordiplom)
University of Washington, Dept. of Pediatrics and Immunology, Senior Post-Doctoral Fellow
Harvard Medical School / Beth-Israel Hospital, Dept. of Pathology, Post-Doctoral Fellow


Perraud A.-L., Takanishi CL, Shen B, Kang S, Smith MK, Schmitz C, Knowles HM, Ferraris D, Li W, Zhang J, Stoddard BL, Scharenberg AM.: Accumulation of free ADP-ribose from mitochondria mediates oxidative stress-induced gating of TRPM2 cation channels, J Biol Chem 280: 6138-6148, 2005.

Schmitz C. *, Perraud A.-L. *, Johnson C. O., Inabe K., Smith M. K., Penner R., Kurosaki T., Fleig A., Scharenberg A. M.: Regulation of vertebrate cellular Mg2+ homeostasis by TRPM7, Cell 114(2):191-200, 2003.

Perraud A.-L., Shen B., Dunn C. A., Rippe K., Smith M. K., Bessman M. J., Stoddard B. L., Scharenberg, A. M.: NUDT9, a member of the nudix hydrolase family, is an evolutionarily conserved mitochondrial ADP-ribose pyrophosphatase, J Biol Chem 278(3):1794-801, 2003.

Launay P. *, Fleig A. *, Perraud A.-L., Scharenberg, A. M., Penner R., Kinet J.-P.: TRPM4 Is a Ca(2+)-Activated Nonselective Cation Channel Mediating Cell Membrane Depolarization, Cell 109(3): 397-407, 2002.

Perraud A.-L.*, Fleig A.*, Dunn C. A.*, Bagley L. A., Launay P., Schmitz C., Stokes A., Zhu Q., Bessman M. J., Penner R., Kinet J.-P., and Scharenberg A. M.: ADP-ribose gating of the calcium-permeable LTRPC2 channel revealed by Nudix motif homology, Nature 411(6837): 595-599, 2001.

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