Alexandra McCubbrey, PhD

Alexandra McCubbrey
Alexandra McCubbrey, PhD, is a researcher at National Jewish Health. Dr. McCubbrey is in the Division of Pulmonary, Critical Care and Sleep Medicine.
Instructor
Division of Pulmonary, Critical Care & Sleep Medicine
Department of Medicine
Research AreasResearch Areas
  • Cellular Metabolism
  • Efferocytosis
  • Immunology
  • Lung Fibrosis
  • Lung Inflammation
  • Macrophage Biology

Special Interests

My long-term research goals focus on understanding the function of macrophages during lung homeostasis and inflammation. I am interested in the ability of macrophages to perform multiple opposing functions over the course of an inflammatory response: driving inflammation and pathogenic tissue remodeling, as well as promoting resolution and repair. My research has focused on describing macrophage subsets within the lung and understanding signals that trigger macrophage reprogramming, particularly the clearance of dying cells by macrophages, termed efferocytosis.

In ongoing work, I am studying a link between efferocytosis, macrophage metabolism, and reprogramming of macrophage function as it relates to the resolution of inflammation/injury and development of fibrosis in the lung. 

Education

Education
University of Michigan, Ann Arbor, MI, Immunology, PhD
Kalamazoo College, Kalamazoo, MI, Biology, BA

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Contact Information

  • Office: 877.225.5654

 

Locations

  • National Jewish Health Main Campus
    1400 Jackson St.
    Denver, CO 80206

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