Alexandra McCubbrey, PhD

Alexandra McCubbrey
Alexandra McCubbrey, PhD, is a researcher at National Jewish Health. Dr. McCubbrey is in the Division of Pulmonary, Critical Care and Sleep Medicine.
Assistant Professor
Division of Pulmonary, Critical Care & Sleep Medicine
Department of Medicine
Research AreasResearch Areas
  • Cellular Metabolism
  • Efferocytosis
  • Immunology
  • Lung Fibrosis
  • Lung Inflammation
  • Macrophage Biology

Special Interests

My research goals focus on understanding signals that control tissue damage and repair. My lab studies how the immune cells called macrophages perform multiple opposing functions over the course of lung injury: driving inflammation and pathogenic tissue remodeling, as well as promoting resolution and repair. We study how this switch is regulated by macrophage engulfment of dead cells, with particular interest in the involvement of cell metabolism. In ongoing work, we are also studying how the structural cells called fibroblasts recognize dead cells and how this activates the ability of fibroblasts to synthesize collagen following lung injury. 


University of Michigan, Ann Arbor, MI, Immunology, PhD
Kalamazoo College, Kalamazoo, MI, Biology, BA

Website Information

McCubbrey Lab

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  • Office: 877.225.5654

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