Brian Modena
Brian Modena, MD, is an allergist at National Jewish Health. Dr. Modena is in the Division of Allergy & Clinical Immunology.
Associate Professor
Division of Allergy & Clinical Immunology
Department of Medicine

Special Interests

Brian Modena, M.D., M.Sc. is a physician & researcher with trained expertise in Allergy-Immunology. He completed a 2-year Allergy-Immunology clinical fellowship with a focus on treating severe asthma patients at the University of Pittsburgh, a hub for the NIH-funded Severe Asthma Research Program. He obtained a M.Sc. in Clinical & Translational Research at the Scripps Research Institute (TSRI) with a focus in Genomics and Translational research, and joined STSI and TSRI as a joint Assistant Professor in 2016. Joining National Jewish Health in 2018, he now works as a physician and NIH-funded researcher in the field of severe asthma.

His research interest involves the use of mRNA gene expression, epigenetic methylation changes, genetic variation, microbiome changes (‘dysbiosis’) and utilization of new health monitoring technologies to improve biological and clinical understanding of clinical disease, particularly in patients with severe asthma and organ transplantation.


Scripps Research, M.S. Genomic & Translational Research
West Virginia University School of Medicine, Medicine
Virgina Tech, Mechanical Engineering
Scripps Clinic & Green Hospital, Internal Medicine
University of Pittsburgh Medical Center & Children's Hospital, Allergy-Immunology

Awards & Recognition

2016: Awarded the Inaugural American Journal of Transplantation Outstanding Article award by American Society of Transplantation (AST) and American Society of Transplant Surgeons (ASTS).
2016: Chairman’s Award of Research Excellence, Scripps Health, San Diego, CA
2015: "Going the Extra Mile" Teaching Award, University of California San Diego
2015: The Scripps Translational Science Institute’s KL2 Scholar Pilot Award
2014: Scripps Health Pilot Award
2014: The Scripps Translational Science Institute’s KL2 Scholar Pilot Award           
2014: KL2 Clinical Scholar Program Scholarship
2014: Winner of American Academy of Allergy, Asthma, and Immunology National Conference Abstract Competition

Awarded the Inaugural American Journal of Transplantation Outstanding Article award by American Society of Transplantation (AST) and American Society of Transplant Surgeons (ASTS).

Board Certification

2008: Internal Medicine
2014: Allergy-Immunology

Professional Memberships

2012-present: American Academy of Allergy, Asthma and Immunology (AAAAI)
2018-present: American Thoracic Society (ATS)
2015-present: Western Society of Allergy, Asthma and Immunology (WSAAI)


Nathaniel Weathington, Michael E. O’Brien, Josiah Radder, Thomas C. Whisenant, Eugene R. Bleecker, William W. Busse, Serpil C. Erzurum, Benjamin Gaston, Nizar N. Jarjour, Deborah A. Meyers, Jadranka Milosevic, John R. Tedrow, John B. Trudeau, Hesper P. Wong, Wei Wu, Naftali Kaminski, Sally E. Wenzel, Brian D. Modena.  Bronchoalveolar Lavage Cell Gene Expression in Severe Asthma Reveals Mechanisms of Severe Disease and Influences of Medications. American journal of respiratory and critical care medicine 2019, [EPub ahead of print]

Xiuxia Zhou, Carol L. Kinlough, Rebecca P. Hughey, Mingzhu Jin, Hideki Inoue, Emily Etling, Brian D. Modena, Naftali Kaminski, Eugene R. Bleecker, Deborah A. Meyers, Nizar N. Jarjour, John B. Trudeau, Fernando Holguin, Anuradha Ray, and Sally E. Wenzel. Sialylation of MUC4β N-glycans by ST6GAL1 orchestrates human airway epithelial cell differentiation associated with type-2 inflammation. JCI Insight. 2019;4(5):e122475.

Inoue H, Hattori T, Zhou X, Etling EB, Modena BD, Trudeau JB, Holguin F, Wenzel SE. Dysfunctional ErbB2, an EGF receptor family member, hinders repair of airway epithelial cells from asthmatic patients. The Journal of Allergy and Clinical Immunology. 2019 Jan 9 [EPub ahead of print].

Teaching & Professional Positions

Assistant Professor, National Jewish Health

Website Information

Modena Asthma Lab

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Contact Information

  • Office: 877.225.5654



  • National Jewish Health Main Campus
    1400 Jackson St.
    Denver, CO 80206

Patient Ratings

The Patient Rating score is an average of all responses to care provider related questions on our independent rating system, the Press Ganey Patient Satisfaction Survey. This survey is about the patient care experience and does not address crucial characteristics like medical decision-making, prescribing the best therapy, and patient outcomes.

Responses are measured on a scale of 1 to 5, with 5 being the best score. Learn more about our patient satisfaction survey.

Provider showed concern


Spoke using clear language

Provider explained things clearly

Amount of time spent with you

Provider included you in decisions

Confidence in your doctor

Likelihood of recommending this provider


Comments are collected in our Press Ganey Patient Satisfaction Surveys. Patients are de-identified to protect confidentiality and patient privacy. Learn more about our patient satisfaction survey.

National Jewish Health PatientNovember, 2020
I can honestly say that I have never experienced such comprehensive medical care. The depth of knowledge and approach to my care was thoughtful, thorough, and appreciated. I felt listened to every step of the way.

National Jewish Health PatientOctober, 2020
This physician showed not only care, compassion and interest in what my health concerns were he was willing to try and resolve them which is a far cry from what I was receiving prior to coming to National Jewish Health.

National Jewish Health PatientJuly, 2020
He was so well prepared. He looked at my current tests & know what was going on with me BEFORE he saw me. I would recommend him to ANYONE!!

National Jewish Health PatientJune, 2020
I've been extremely impressed with Dr. Modena and his nursing staff.

National Jewish Health PatientApril, 2020
Very impressed by both doctors.

National Jewish Health PatientApril, 2020
[Comment about another provider] I've never had that level of care & attention before.

National Jewish Health PatientFebruary, 2020

National Jewish Health PatientJune, 2019
Affable & compassionate, one of my fave. doctors ever in my lifetime - and I've met/worked with so many - I'm actually glad that circumstances were such that he became my allergist.

National Jewish Health PatientMay, 2019
Good experience.