Systemic Allergic Reaction to SARS-CoV-2 Vaccination

Trial Objective

Systemic Allergic Reaction to SARS-CoV-2 VaccinationThis research is being done to determine whether highly allergic people or people with mast cell disorders (a buildup of the white blood cells that release substances causing symptoms similar to an allergic reaction) are more likely to have an allergic reaction to the new Pfizer-BioNTech and Moderna COVID-19 vaccines than other people. We would also like to understand why some people have allergic reactions to these vaccines.


Active Clinical Trials Currently Recruiting

Who Can Participate

Individuals who are 12 years of age or older and either have a history of serious allergic reaction, have a mast cell disorder, or have a history of no severe allergies.

Age: 12+    Gender: Any Gender

Estimated Time Commitment

29-43 days with 2-4 clinic visits and 3-4 phone calls

Payment & Reimbursement  

Payment: Provided

Travel Reimbursement: Not Available

Trial Contact

For more information, contact:

Ashley Kohlhepp

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Trial Location

National Jewish Main Campus, Denver, CO

Trial Sponsors

National Institute of Allergy and Infectious Disease (NIAID)


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