Potential Reduction of Cystic Fibrosis Pulmonary Flare-Ups

Trial Objective

Potential Reduction of Cystic Fibrosis Pulmonary Flare-UpsThe purpose of this research study is to determine if an investigational medication can reduce inflammation, tissue scarring, and the number of pulmonary exacerbations, or episodes when breathing is more difficult, in people with cystic fibrosis (CF).

Our researchers are studying if two different doses of this medication can be taken safely without causing too many side effects. Current treatments for pulmonary exacerbations (inhaled, oral or intravenous antibiotics and hospitalization) and therapies for inflammation (corticosteroids, antibiotics and high-dose ibuprofen) can cause short- and long-term toxic effects in the body, and may or may not be effective. This medication may stop chronic inflammation and the scarring it can produce without suppressing the immune system.

Enrollment

This trial is active and currently recruiting.

Who Can Participate

People with cystic fibrosis who are 12 or older may be eligible to participate.

Age: 12+    Gender: Any Gender


Estimated Time Commitment

9 visits (15 hours over about 32 weeks)

This study involves 28 weeks of active dosing with the study drug plus a safety follow-up visit at Week 32.



Compensation

Provided

Trial Contact

For more information, contact:

Alexandria Leonhardt

Alexandria Leonhardt
303.398.1453

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Trial Location

National Jewish Main Campus, Denver, CO

Trial Sponsors

Corbus Pharmaceuticals, Inc.

Principal Investigators


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