New Medication for Early-Stage Non-small cell Lung Cancer

Trial Objective

New Medication for Early-Stage Non-small cell Lung CancerResearchers are testing a medication called atezolizumab and its effects on early-stage non-small cell lung cancer (NSCLC). Atezolizumab is an experimental immunotherapy medicine, which is a man-made antibody.

Antibodies are used by the immune system to identify and destroy bacteria, viruses and tumor cells. Atezolizumab is approved to treat advanced cancer of the bladder and lung, and researchers believe it may help people who have early-stage NSCLC. In this study, participants will get either atezolizumab and chemotherapy or a placebo and chemotherapy before undergoing surgery to remove their tumor.


New enrollment for this trial is temporarily paused

Who Can Participate

 Adults diagnosed with early-stage non-small cell lung cancer (NSCLC) that can be surgically removed.

Age: 18+    Gender: Any Gender

Estimated Time Commitment

The screening period may last up to 6 weeks and involve up to 2 visits to the clinic.

One group will receive pre-surgery treatment for up to 12 weeks, then undergo surgery, followed by taking atezolizumab for up to 48 weeks. The other group will receive pre-surgery treatment for up to 12 weeks, undergo surgery and then be given the best supportive care and monitoring. Maximum of clinic visits would be once a week.

Payment & Reimbursement  

Payment: Not Provided

Travel Reimbursement: Available

Trial Contact

For more information, contact:

Jami Henriksen, Trial Coordinator

Jami Henriksen

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Trial Location

National Jewish Main Campus, Denver, CO

Trial Sponsors

F. Hoffmann-La Roche Ltd

Principal Investigators


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After limiting clinical research activity due to safety concerns about COVID-19, we are now restarting clinical research in stages. If you are interested in any of the clinical trials posted on our website, please request trial information. We will respond and share the timing for enrollment resuming. Learn More