The purpose of this study is to see if a medication called tezepelumab is effective in treating severe asthma and if it causes side effects.
Tezepelumab is a man-made antibody, a protein produced by specific cells in the immune system that react to a substance that the body sees as foreign, such as bacteria or viruses. Tezapelumab reacts with a substance called thymic stromal lymphopoietin (TSLP), which is known to play a role in causing asthma. The Food and Drug Administration (FDA) has not approved tezepelumab for the treatment of asthma. Its use in this study is considered investigational.