Link Between Reflux & Pulmonary Disease

Trial Objective

During this study, healthy individuals and people with reflux-related pulmonary disease will receive an esophageal stress test. The goal of the test is to see if those with certain pulmonary diseases (such as asthma, COPD, bronchiectasis, ILD and NTM) have a higher risk of developing Supraesophageal Reflux Disease (SERD).

Link Between Reflux & Pulmonary Disease

Researchers are trying to recreate SERD symptoms in healthy participants by coating their esophagus with a lidocaine spray. Using the data collected, researchers hope to predict which pulmonary diseases are predisposed to SERD. All participants will fill out questionnaires and undergo a variety of tests that look at the esophagus. Two biopsy samples will be collected. Healthy participants will require a follow up visit for further testing that will be compared to the original results.


This trial is active and currently recruiting.

How to Participate

For more information contact Cole Waliczek at 303.270.2844 or complete the form below.

Who Can Participate

Healthy adults and adult patients with pulmonary disease.

Estimated Time Commitment

Healthy individuals: Two 2-hour visits. Pulmonary Disease participants: One 2-hour visit.

Trial Location

National Jewish Main Campus, Denver, CO






Any Gender

Principal Investigators

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