During this study, healthy individuals and people with reflux-related pulmonary disease will receive an esophageal stress test. The goal of the test is to see if those with certain pulmonary diseases (such as asthma, COPD, bronchiectasis, ILD and NTM) have a higher risk of developing Supraesophageal Reflux Disease (SERD).
Researchers are trying to recreate SERD symptoms in healthy participants by coating their esophagus with a lidocaine spray. Using the data collected, researchers hope to predict which pulmonary diseases are predisposed to SERD. All participants will fill out questionnaires and undergo a variety of tests that look at the esophagus. Two biopsy samples will be collected. Healthy participants will require a follow up visit for further testing that will be compared to the original results.