Healthy Participants Needed for Lung Disease Study Request More Information Trial Objective The purpose of this study is to learn more about new ways to detect injury or disease in the small airways of the lung. Spirometry, the most commonly used lung function test, often does not detect disease in small airways. A type of breathing test called the lung clearance index (LCI) has shown promise in detecting small airway diseases in those with conditions such as cystic fibrosis. We will conduct LCI testing in people with chronic lung disease, as well as healthy participants with no history of lung disease, to see if this technique helps to detect abnormalities in small airways. We also will conduct spirometry testing and compare the results to LCI testing to determine if LCI is more effective in detecting abnormal lung function. Enrollment New enrollment for this trial is temporarily paused Who Can Participate Adults who do not have a history of chronic lung conditions such as asthma and chronic obstructive pulmonary disease (COPD). Age: 18+ Gender: Any Gender Estimated Time Commitment 60-90 minute session Participants will complete a brief questionnaire, as well as spirometry and lung clearance index (LCI) tests. × Payments are intended to compensate the participant for their time and effort during the study. Payments are typically given to the participant at the end of each completed study visit. Reimbursements are intended to compensate the participant for travel-related expenses. They must be approved by the study staff and require you to turn in receipts. Travel reimbursement will vary from study to study. Payment & Reimbursement Payment: Provided Travel Reimbursement: Not Available Trial Contact For more information, contact: Lauren Zell-Baran 303.398.1187 Request More Information Trial Location National Jewish Main Campus, Denver, CO Trial Sponsors Fund 30 Principal Investigators Cecile Rose, MD, MPH + × Cecile Rose, MD, MPH Professor Director, Division of Environmental & Occupational Health Sciences Department of Medicine Division of Environmental & Occupational Health Sciences View Full Profile Patient Rating 4.8 out of 5 stars Make an Appoinment Co-Investigators E Gottschall, MD + × E Gottschall, MD Associate Professor Department of Medicine Division of Environmental & Occupational Health Sciences View Full Profile Make an Appoinment Richard Meehan, MD, FACP + × Richard Meehan, MD, FACP Professor, Department of Medicine Division of Rheumatology Co-Director, Post-Deployment Lung Health Center Autoimmune Lung Center View Full Profile Make an Appoinment Silpa Krefft, MD, MPH + × Silpa Krefft, MD, MPH Assistant Professor Department of Medicine Division of Environmental & Occupational Health Sciences View Full Profile Make an Appoinment Request More Information Due to concerns around COVID-19 and our focus on helping to meet this momentous challenge, we have temporarily paused enrollment for this trial.
Trial Objective The purpose of this study is to learn more about new ways to detect injury or disease in the small airways of the lung. Spirometry, the most commonly used lung function test, often does not detect disease in small airways. A type of breathing test called the lung clearance index (LCI) has shown promise in detecting small airway diseases in those with conditions such as cystic fibrosis. We will conduct LCI testing in people with chronic lung disease, as well as healthy participants with no history of lung disease, to see if this technique helps to detect abnormalities in small airways. We also will conduct spirometry testing and compare the results to LCI testing to determine if LCI is more effective in detecting abnormal lung function.