The purpose of this study is to evaluate an investigational medication, INCB018424, in treating eczema, or atopic dermatitis, in children.
This topical cream belongs to a new class of medications called phosphate creams. By blocking proteins that are overactive in the skin and make eczema worse, INCB018424 may reduce inflammation. INCB018424 has been safely used in clinical studies on psoriasis, a skin condition that also is characterized by inflammation. Three different strengths of INCB018424 cream are being studied. This study is open-label, which means that the participants and their study doctor will know what strength of cream they are receiving. Participants will apply the cream twice daily.