Clinical Trials Search

Our researchers are currently in need of adult and pediatric study participants to help us pursue better treatments and cures. Participants may receive medical evaluations and procedures, study medication, disease-related education and possible financial compensation for time, travel and participation.

 

Select a Condition or Specialty



All Clinical Trials

SEAL Study: Stopping Eczema and Allergy

Can allergies be prevented in infants? Researchers want to know if keeping a baby’s skin healthy and hydrated with moisturizer will prevent the child from developing allergies such as food allergies. Learn how you and your child can help researchers.

  • Gender: Any Gender
  • Ages: Newborn to 10-weeks-old
  • Compensation: Provided
  • Time Required: Three years, with six clinic visits and weekly or monthly phone calls with researchers

Skin Care Impact on Skin Barrier

Infants and children up to age 18 are needed for a research study to determine if following a proper skin care routine can change the characteristics of the skin. If your child has eczema, asthma or is healthy, they may be able to help researchers with this important study.

  • Gender: Any Gender
  • Ages: 0-18
  • Compensation: Provided
  • Time Required: 1-3 clinic visits over three weeks

Response to COVID-19 Vaccines in People with Chronic Conditions

National Jewish Health researchers are studying the antibody response to COVID-19 vaccines in people with chronic conditions.

  • Gender: Any Gender
  • Ages: 18+
  • Compensation: Provided
  • Time Required: Up to 4 visits over about 1 year

Healthy People Needed for Sarcoidosis Research

Researchers are working to understand the different ways sarcoidosis, a disease that causes scarring in the lungs, develops.

  • Gender: Any Gender
  • Ages: 18-80
  • Compensation: Provided
  • Time Required: Up to 2 visist

Skin, Airway & Esophageal Epithelial Barriers in Youth

Researchers want to better understand if the causes of asthma, eczema, food allergies, eosinophilic esophagitis and GERD can be determined at a cellular level.

  • Gender: Any Gender
  • Ages: 2-25
  • Compensation: Not Provided
  • Time Required: Up to 3 visits for a total 1 hour

Creating Asthma Measurements through the MORRE Study

Researchers want to find new measures of asthma control by tracking each participant’s asthma symptoms and response to omalizumab, while collecting data with a FitBit® and smartphone.

  • Gender: Any Gender
  • Ages: 18-85
  • Compensation: Provided
  • Time Required: Not Specified

Improving Asthma Treatment Using Video Chat

Can frequent video calls with a pharmacist via smart phone or computer help 14-30-year-olds take their prescribed asthma medications regularly and have fewer asthma symptoms?

  • Gender: Any Gender
  • Ages: Not Specified
  • Compensation: Provided
  • Time Required: Not Specified

SIMPLIFY Study for Cystic Fibrosis

In the SIMPLIFY study, researchers are trying to determine whether or not it is safe for people with cystic fibrosis (CF) to stop taking either inhaled hypertonic saline or Pulmozyme® (dornase alfa) if they are also taking Trikafta™.

  • Gender: Any Gender
  • Ages: 12+
  • Compensation: Provided
  • Time Required: 4 study visits, 1 phone call and daily questionnaires over 8 weeks

Biomarkers & Hypersensitivity Pneumonitis Progression

Are biomarkers in the blood of patients with hypersensitivity pneumonitis (HP) predictive? Researchers understand if biomarkers can help doctors understand how quickly the disease will progress

  • Gender: Any Gender
  • Ages: 18-80
  • Compensation: Not Provided
  • Time Required: 5 total visits, each lasting 2-4 hours

Systemic Allergic Reaction to SARS-CoV-2 Vaccination

Volunteers needed to determine whether highly allergic people or people with mast cell disorders are more likely to have an allergic reaction to COVID-19 vaccines than others.

  • Gender: Any Gender
  • Ages: 12+
  • Compensation: Provided
  • Time Required: 29-43 days with 2-4 clinic visits and 3-4 phone calls

Does Keto Diet Help Reverse Heart Failure with Preserved Ejection Fraction?

Studies have shown that weight loss can improve heart function. Researchers want to see if a ketogenic diet is an effective treatment for heart failure with preserved ejection fraction.

  • Gender: Any Gender
  • Ages: 21-80
  • Compensation: Provided
  • Time Required: Not Specified

Effects of Investigational Pulmonary Fibrosis Drug

If you have pulmonary fibrosis, you may be able to help researchers understand if an investigational drug known as BMS-986278 can prevent or slow down pulmonary fibrosis progression.

  • Gender: Any Gender
  • Ages: IPF patients: 40+ PF-ILD patients: 21+
  • Compensation: Provided
  • Time Required: 34 weeks

SUNBEAM: Studying Allergy Development in Babies

Why do babies develop food allergies and eczema? Researchers are studying factors before birth and through age 3 that may influence the development of allergic conditions.

  • Gender: Any Gender
  • Ages: 18+
  • Compensation: Provided
  • Time Required: Up to 3 years of participation

CHARM Study for Asthma

Researchers want to improve medical care for asthmatics with new mobile health technologies. Study participants will use at-home technologies to track and record health data and participate in surveys and questionnaires about their health.

  • Gender: Any Gender
  • Ages: 18+
  • Compensation: Provided
  • Time Required: Not Specified

Blood Test and Lung Nodule Treatment

Researchers want to know if a new blood test for patients with lung nodules may reduce the need for physicians to order lung nodule biopsies or invasive procedures.

  • Gender: Any Gender
  • Ages: 40+
  • Compensation: Provided
  • Time Required: Up to 2 years, with a total of 5 clinic visits

Water Loss in the Skin of Pediatric Eczema Patients

Researchers want to know how much water is lost from the skin of pediatric patients with atopic dermatitis (eczema) before and after using the medication dupilumab.

  • Gender: Any Gender
  • Ages: 6-12
  • Compensation: Provided
  • Time Required: Up to 12 visits over 8 months

Medication Aims to Improve Moderate COVID-19 Symptoms

If you currently are experiencing moderate COVID-19 symptoms, our researchers need your help to determine if an investigational drug can safely and effectively improve symptoms of mild COVID-19, and potentially shorten how long a person feels ill from the disease.

  • Gender: Any Gender
  • Ages: 18+
  • Compensation: Provided
  • Time Required: Not Specified

Skin Reactions to Cancer Immunotherapy

Adults with cancer who are receiving immunotherapy are needed for a new research study to understand how immunotherapy changes the body’s immune response leading to skin reactions.

  • Gender: Any Gender
  • Ages: 18+
  • Compensation: Provided
  • Time Required: Up to 2 visits over 3 months, with possible phone follow-up after 12 months depending on cancer...

Potential New Treatment for Alpha-1 Antitrypsin Deficiency

Researchers want to see if a new drug, alvelestat, improves the symptoms of lung disease caused by COPD due to alpha-1 antitrypsin deficiency (AATD), as well as symptoms of AATD.

  • Gender: Any Gender
  • Ages: 18-80
  • Compensation: Provided
  • Time Required: Up to 5 months

Understanding Skin Problems from Eczema and Food Allergies

Researchers are studying the differences in the skin and immune cells of people with food allergies and eczema, and those without.

  • Gender: Any Gender
  • Ages: 1-65
  • Compensation: Provided
  • Time Required: 1-2 visits, approximately 5 hours

Lymphocytes & Sarcoidosis Inflammation

Our researchers want to learn more about the different types of sarcoidosis and how it develops. If you’re an adult with sarcoidosis and you are not on immunosuppressive therapy, you may be able to help.

  • Gender: Any Gender
  • Ages: 18+
  • Compensation: Provided
  • Time Required: 2 visits, 1 blood draw and one bronchoscopy (optional)

Improving Treatment for IPF

Researchers want to know if a new medication, Saracatinib, is a more safe and effective treatment for Idiopathic Pulmonary Fibrosis (IPF) when compared to treatments that are currently available.

  • Gender: Any Gender
  • Ages: 40+
  • Compensation: Not Provided
  • Time Required: 8 visits to the study center, plus phone visits to review lab results

Alternative Treatment for Insomnia in Adults

Adults ages 21 and older with chronic insomnia who have taken sleep medication for more than one year are needed for a clinical trial.

  • Gender: Any Gender
  • Ages: 21+
  • Compensation: Provided
  • Time Required: Up to 15 visits to our sleep clinic over a 12-month period

Understanding Allergy Development in Infants

Researchers want to know what causes food allergies, eczema and wheezing in infants. If you’re pregnant, you may be able to help find the answer.

  • Gender: Any Gender
  • Ages: 0-50
  • Compensation: Provided
  • Time Required: 3 in person visits and 1 telephone call, followed by 4 optional visits

PrecISE Severe Asthma Interventions

If you have uncontrolled asthma you may qualify for a study to help researchers understand how to treat different types of severe asthma using precision medicine.

  • Gender: Any Gender
  • Ages: 12+
  • Compensation: Provided
  • Time Required: 3 phases, approximately 9 visits per phase for up to 2 years

Can Pembrolizumab (MK3475) with SBRT Treatment Stop or Slow Non-Small Cell Lung Cancer?

Patients with medically inoperable stage I/IIA non-small cell lung cancer (NSCLC) who have not received prior anticancer therapy for lung cancer, may qualify for a clinical trial investigating if the combination of pembrolizumab (MK-3475) and Stereotactic Body Radiation Therapy (SBRT) may help...

  • Gender: Any Gender
  • Ages: 18+
  • Compensation: Provided
  • Time Required: Up to 7 years

Silicosis Registry

If you’ve been exposed to silica dust, like stone and concrete, you may have developed a silica-related disease. National Jewish Health is creating a registry for silicosis and related diseases in order to better understand their risk factors and prevention.

  • Gender: Any Gender
  • Ages: 18+
  • Compensation: Provided
  • Time Required: 1 clinic or phone visit lasting 1 hour, as well as 15 minute follow-up phone interviews once a...

COPD Patient Knowledge

National Jewish Health researchers want to understand what people with COPD know about their disease.

  • Gender: Any Gender
  • Ages: 18-99
  • Compensation: Provided
  • Time Required: 2-3 visits approximately 60 minutes in length each

Investigational Treatment for Food Allergies

Our researchers are trying to determine if a study medication called omalizumab alone or combined with oral immunotherapy may help people with multiple food allergies.

  • Gender: Any Gender
  • Ages: Not Specified
  • Compensation: Provided
  • Time Required: This is a multi-stage study, with an individual study participation of up to 4 years and 8 months...

Predicting ILD from Hypersensitivity Pneumonitis

Anyone with hypersensitivity pneumonitis may qualify for this observational study and help researchers find patterns for predicting ILD.

  • Gender: Any Gender
  • Ages: 18-90
  • Compensation: Not Provided
  • Time Required: Clinic visits every 6 months over approximately 2 years (4 visits total)

Understanding the Genetics of Asthma

Doctors today are still learning about the causes of asthma. With just an hour of your time, you can help our researchers look deeper into the genetics of the disease and develop better treatment options

  • Gender: Any Gender
  • Ages: 18-75
  • Compensation: Provided
  • Time Required: 1-2 office visits totaling up to 1.5 hours

Atopic Dermatitis & Skin Infections

National Jewish Health researchers are trying to determine why people with atopic dermatitis or eczema are more susceptible to bacterial infections. Learn how you can participate in our research study.

  • Gender: Any Gender
  • Ages: 18-65
  • Compensation: Provided
  • Time Required: Up to 3 visits or approximately 3 hours

Treating Insomnia & OSA with Cognitive Behavioral Therapy

Does your mind race at night when you're trying to sleep? Our researchers are studying how people with insomnia and obstructive sleep apnea can benefit from cognitive behavioral therapy, a goal-oriented type of treatment that aims to identify and change inaccurate or negative thinking patterns...

  • Gender: Any Gender
  • Ages: 21-80
  • Compensation: Provided
  • Time Required: Not Specified

Identifying Characteristics and Patterns of Asthma

Our researchers are working to identify the clinical, physiologic, genetic and molecular characteristics of asthmatics.

  • Gender: Any Gender
  • Ages: 5+
  • Compensation: Provided
  • Time Required: 2-4 office visits and up to 3 follow up phone calls

Impact of Triple Combination Therapy for People with CF with Sinusitis

In addition to its impact on lung function and sweat chloride, a new medication regimen may improve chronic sinusitis signs and symptoms and sense of smell for people with CF.

  • Gender: Any Gender
  • Ages: 18-80
  • Compensation: Provided
  • Time Required: 6 months

New Trial Medication for Pulmonary Arterial Hypertension

By adding a new investigational Pulmonary Arterial Hypertension (PAH) medication to your current therapy, you could experience relaxed and widened artery walls.

  • Gender: Any Gender
  • Ages: 18-75
  • Compensation: Provided
  • Time Required: Up to 42 months

Healthy Adults Needed for Beryllium Disease Study

By participating in our study, you can help forward research on lung disease. Our researchers are hoping to learn more about the blood cells involved in the development of scarring lung diseases and create new treatment therapies.

  • Gender: Any Gender
  • Ages: 18-80
  • Compensation: Provided
  • Time Required: 5 hours over 2 visits

New Medication for Early-Stage Non-small cell Lung Cancer

Already approved for advanced non-small cell lung cancer, atezolizumab is a drug that may help those with early-stage lung cancer, as well. Participants in this clinical trial may take atezolizumab in conjunction with their chemotherapy treatments.

  • Gender: Any Gender
  • Ages: 18+
  • Compensation: Not Provided
  • Time Required: The screening period may last up to 6 weeks and involve up to 2 visits to the clinic.

Hypersensitivity Pneumonitis and the Immune System

Help us look at how specific white blood cells are associated with hypersensitivity pneumonitis (HP) and impact how your disease affects you.

  • Gender: Any Gender
  • Ages: 18-80
  • Compensation: Provided
  • Time Required: Approximately 9 hours over 3 study visits

Lung Injury from Military Deployment

The purpose of this study is to learn more about lung disease found in contractors and U.S. military personnel serving in Iraq and Afghanistan after September 11, 2001.

  • Gender: Any Gender
  • Ages: 18-70
  • Compensation: Provided
  • Time Required: 1 to 2 visits

Link Between Rheumatoid Arthritis & Lung Disease

Our researchers are trying to understand the connection, as well as how to prevent and treat lung disease in RA patients.

  • Gender: Any Gender
  • Ages: 18+
  • Compensation: Not Provided
  • Time Required: 6 in-person visits, performed every year over 4 years

ILD & Early Rheumatoid Arthritis

Our researchers are trying to understand how interstitial lung disease (ILD) develops in people with rheumatoid arthritis (RA), and how it may impact their quality of life.

  • Gender: Any Gender
  • Ages: 18-90
  • Compensation: Not Provided
  • Time Required: 5 in-person visits over 18 months

Idiopathic Pulmonary Fibrosis (IPF) & GERD

The purpose of this study is to measure and accurately identify the presence and severity of gastroesphageal reflux disease (GERD), commonly called acid reflux, in idiopathic pulmonary fibrosis (IPF) patients using the Supraglottic Index (SGI).

  • Gender: Any Gender
  • Ages: 40-95
  • Compensation: Provided
  • Time Required: 5 visits over a 6-month period, visits are every 3 months

Current & Former Smokers Needed for Lung Research Study

Our researchers are studying the lungs of current and former smokers to understand how to improve the diagnosis and treatment of Chronic Obstructive Pulmonary Disease (COPD), a disease that is common among smokers. You do not need to have COPD to participate in this study.

  • Gender: Any Gender
  • Ages: 55-77
  • Compensation: Provided
  • Time Required: 1-2 hour visit (can be scheduled immediately after your CT if there is space available)

Immune Pathways & Development of Sarcoidosis

If you are an adult with sarcoidosis who is not on immunosuppressive therapy, you may be able to help our researchers learn more about different types of sarcoidosis and how it develops.

  • Gender: Any Gender
  • Ages: 18+
  • Compensation: Provided
  • Time Required: Up to 2 visits

Mineral Dust & Lung Disease

Our researchers are studying lung diseases that develop from inhaling mineral dust over time. Although the cause of diseases such as "black lung" are known, it is not well understood why some people develop these diseases and others don't.

  • Gender: Any Gender
  • Ages: 18+
  • Compensation: Not Provided
  • Time Required: Not Specified

Healthy Participants Needed for Lung Disease Study

Are you 18 or older with no history of chronic lung conditions? You may be able to help our researchers better understand lung disease. Compensation provided.

  • Gender: Any Gender
  • Ages: 18+
  • Compensation: Provided
  • Time Required: 60-90 minute session

Investigational Medication Sirolimus for Lymphangioleiomyomatosis (LAM)

The purpose of this study is to see if a drug called sirolimus slows development of lymphangioleiomyomatosis (LAM), a lung disease in which abnormal cells growing inside the lungs prevent them from working properly.

  • Gender: Any Gender
  • Ages: 18+
  • Compensation: Provided
  • Time Required: 2 years

Can Investigational Drug Benefit Lung Cancer Surgery Patients?

The purpose of this clinical trial is to see if it better to receive an investigational medication or no further treatment after surgery (and possibly chemotherapy) to remove non-small cell lung cancer (NSCLC).

  • Gender: Any Gender
  • Ages: 18+
  • Compensation: Not Provided
  • Time Required: Up to 12 months

Pulmonary Fibrosis & Genetic Factors

The purpose of this study is to investigate inherited genetic factors that play a role in the development of familial pulmonary fibrosis and to identify a group of genes that predispose individuals to develop pulmonary fibrosis.

  • Gender: Any Gender
  • Ages: Not Specified
  • Compensation: Not Provided
  • Time Required: Not Specified

Adult Clinical Trials

Skin Care Impact on Skin Barrier

Infants and children up to age 18 are needed for a research study to determine if following a proper skin care routine can change the characteristics of the skin. If your child has eczema, asthma or is healthy, they may be able to help researchers with this important study.

  • Gender: Any Gender
  • Ages: 0-18
  • Compensation: Provided
  • Time Required: 1-3 clinic visits over three weeks

Response to COVID-19 Vaccines in People with Chronic Conditions

National Jewish Health researchers are studying the antibody response to COVID-19 vaccines in people with chronic conditions.

  • Gender: Any Gender
  • Ages: 18+
  • Compensation: Provided
  • Time Required: Up to 4 visits over about 1 year

Healthy People Needed for Sarcoidosis Research

Researchers are working to understand the different ways sarcoidosis, a disease that causes scarring in the lungs, develops.

  • Gender: Any Gender
  • Ages: 18-80
  • Compensation: Provided
  • Time Required: Up to 2 visist

Skin, Airway & Esophageal Epithelial Barriers in Youth

Researchers want to better understand if the causes of asthma, eczema, food allergies, eosinophilic esophagitis and GERD can be determined at a cellular level.

  • Gender: Any Gender
  • Ages: 2-25
  • Compensation: Not Provided
  • Time Required: Up to 3 visits for a total 1 hour

Creating Asthma Measurements through the MORRE Study

Researchers want to find new measures of asthma control by tracking each participant’s asthma symptoms and response to omalizumab, while collecting data with a FitBit® and smartphone.

  • Gender: Any Gender
  • Ages: 18-85
  • Compensation: Provided
  • Time Required: Not Specified

Improving Asthma Treatment Using Video Chat

Can frequent video calls with a pharmacist via smart phone or computer help 14-30-year-olds take their prescribed asthma medications regularly and have fewer asthma symptoms?

  • Gender: Any Gender
  • Ages: Not Specified
  • Compensation: Provided
  • Time Required: Not Specified

SIMPLIFY Study for Cystic Fibrosis

In the SIMPLIFY study, researchers are trying to determine whether or not it is safe for people with cystic fibrosis (CF) to stop taking either inhaled hypertonic saline or Pulmozyme® (dornase alfa) if they are also taking Trikafta™.

  • Gender: Any Gender
  • Ages: 12+
  • Compensation: Provided
  • Time Required: 4 study visits, 1 phone call and daily questionnaires over 8 weeks

Biomarkers & Hypersensitivity Pneumonitis Progression

Are biomarkers in the blood of patients with hypersensitivity pneumonitis (HP) predictive? Researchers understand if biomarkers can help doctors understand how quickly the disease will progress

  • Gender: Any Gender
  • Ages: 18-80
  • Compensation: Not Provided
  • Time Required: 5 total visits, each lasting 2-4 hours

Systemic Allergic Reaction to SARS-CoV-2 Vaccination

Volunteers needed to determine whether highly allergic people or people with mast cell disorders are more likely to have an allergic reaction to COVID-19 vaccines than others.

  • Gender: Any Gender
  • Ages: 12+
  • Compensation: Provided
  • Time Required: 29-43 days with 2-4 clinic visits and 3-4 phone calls

Does Keto Diet Help Reverse Heart Failure with Preserved Ejection Fraction?

Studies have shown that weight loss can improve heart function. Researchers want to see if a ketogenic diet is an effective treatment for heart failure with preserved ejection fraction.

  • Gender: Any Gender
  • Ages: 21-80
  • Compensation: Provided
  • Time Required: Not Specified

Effects of Investigational Pulmonary Fibrosis Drug

If you have pulmonary fibrosis, you may be able to help researchers understand if an investigational drug known as BMS-986278 can prevent or slow down pulmonary fibrosis progression.

  • Gender: Any Gender
  • Ages: IPF patients: 40+ PF-ILD patients: 21+
  • Compensation: Provided
  • Time Required: 34 weeks

SUNBEAM: Studying Allergy Development in Babies

Why do babies develop food allergies and eczema? Researchers are studying factors before birth and through age 3 that may influence the development of allergic conditions.

  • Gender: Any Gender
  • Ages: 18+
  • Compensation: Provided
  • Time Required: Up to 3 years of participation

CHARM Study for Asthma

Researchers want to improve medical care for asthmatics with new mobile health technologies. Study participants will use at-home technologies to track and record health data and participate in surveys and questionnaires about their health.

  • Gender: Any Gender
  • Ages: 18+
  • Compensation: Provided
  • Time Required: Not Specified

Blood Test and Lung Nodule Treatment

Researchers want to know if a new blood test for patients with lung nodules may reduce the need for physicians to order lung nodule biopsies or invasive procedures.

  • Gender: Any Gender
  • Ages: 40+
  • Compensation: Provided
  • Time Required: Up to 2 years, with a total of 5 clinic visits

Medication Aims to Improve Moderate COVID-19 Symptoms

If you currently are experiencing moderate COVID-19 symptoms, our researchers need your help to determine if an investigational drug can safely and effectively improve symptoms of mild COVID-19, and potentially shorten how long a person feels ill from the disease.

  • Gender: Any Gender
  • Ages: 18+
  • Compensation: Provided
  • Time Required: Not Specified

Skin Reactions to Cancer Immunotherapy

Adults with cancer who are receiving immunotherapy are needed for a new research study to understand how immunotherapy changes the body’s immune response leading to skin reactions.

  • Gender: Any Gender
  • Ages: 18+
  • Compensation: Provided
  • Time Required: Up to 2 visits over 3 months, with possible phone follow-up after 12 months depending on cancer...

Potential New Treatment for Alpha-1 Antitrypsin Deficiency

Researchers want to see if a new drug, alvelestat, improves the symptoms of lung disease caused by COPD due to alpha-1 antitrypsin deficiency (AATD), as well as symptoms of AATD.

  • Gender: Any Gender
  • Ages: 18-80
  • Compensation: Provided
  • Time Required: Up to 5 months

Understanding Skin Problems from Eczema and Food Allergies

Researchers are studying the differences in the skin and immune cells of people with food allergies and eczema, and those without.

  • Gender: Any Gender
  • Ages: 1-65
  • Compensation: Provided
  • Time Required: 1-2 visits, approximately 5 hours

Lymphocytes & Sarcoidosis Inflammation

Our researchers want to learn more about the different types of sarcoidosis and how it develops. If you’re an adult with sarcoidosis and you are not on immunosuppressive therapy, you may be able to help.

  • Gender: Any Gender
  • Ages: 18+
  • Compensation: Provided
  • Time Required: 2 visits, 1 blood draw and one bronchoscopy (optional)

Improving Treatment for IPF

Researchers want to know if a new medication, Saracatinib, is a more safe and effective treatment for Idiopathic Pulmonary Fibrosis (IPF) when compared to treatments that are currently available.

  • Gender: Any Gender
  • Ages: 40+
  • Compensation: Not Provided
  • Time Required: 8 visits to the study center, plus phone visits to review lab results

PrecISE Severe Asthma Interventions

If you have uncontrolled asthma you may qualify for a study to help researchers understand how to treat different types of severe asthma using precision medicine.

  • Gender: Any Gender
  • Ages: 12+
  • Compensation: Provided
  • Time Required: 3 phases, approximately 9 visits per phase for up to 2 years

Can Pembrolizumab (MK3475) with SBRT Treatment Stop or Slow Non-Small Cell Lung Cancer?

Patients with medically inoperable stage I/IIA non-small cell lung cancer (NSCLC) who have not received prior anticancer therapy for lung cancer, may qualify for a clinical trial investigating if the combination of pembrolizumab (MK-3475) and Stereotactic Body Radiation Therapy (SBRT) may help...

  • Gender: Any Gender
  • Ages: 18+
  • Compensation: Provided
  • Time Required: Up to 7 years

Silicosis Registry

If you’ve been exposed to silica dust, like stone and concrete, you may have developed a silica-related disease. National Jewish Health is creating a registry for silicosis and related diseases in order to better understand their risk factors and prevention.

  • Gender: Any Gender
  • Ages: 18+
  • Compensation: Provided
  • Time Required: 1 clinic or phone visit lasting 1 hour, as well as 15 minute follow-up phone interviews once a...

COPD Patient Knowledge

National Jewish Health researchers want to understand what people with COPD know about their disease.

  • Gender: Any Gender
  • Ages: 18-99
  • Compensation: Provided
  • Time Required: 2-3 visits approximately 60 minutes in length each

Investigational Treatment for Food Allergies

Our researchers are trying to determine if a study medication called omalizumab alone or combined with oral immunotherapy may help people with multiple food allergies.

  • Gender: Any Gender
  • Ages: Not Specified
  • Compensation: Provided
  • Time Required: This is a multi-stage study, with an individual study participation of up to 4 years and 8 months...

Predicting ILD from Hypersensitivity Pneumonitis

Anyone with hypersensitivity pneumonitis may qualify for this observational study and help researchers find patterns for predicting ILD.

  • Gender: Any Gender
  • Ages: 18-90
  • Compensation: Not Provided
  • Time Required: Clinic visits every 6 months over approximately 2 years (4 visits total)

Treating Insomnia & OSA with Cognitive Behavioral Therapy

Does your mind race at night when you're trying to sleep? Our researchers are studying how people with insomnia and obstructive sleep apnea can benefit from cognitive behavioral therapy, a goal-oriented type of treatment that aims to identify and change inaccurate or negative thinking patterns...

  • Gender: Any Gender
  • Ages: 21-80
  • Compensation: Provided
  • Time Required: Not Specified

Impact of Triple Combination Therapy for People with CF with Sinusitis

In addition to its impact on lung function and sweat chloride, a new medication regimen may improve chronic sinusitis signs and symptoms and sense of smell for people with CF.

  • Gender: Any Gender
  • Ages: 18-80
  • Compensation: Provided
  • Time Required: 6 months

New Trial Medication for Pulmonary Arterial Hypertension

By adding a new investigational Pulmonary Arterial Hypertension (PAH) medication to your current therapy, you could experience relaxed and widened artery walls.

  • Gender: Any Gender
  • Ages: 18-75
  • Compensation: Provided
  • Time Required: Up to 42 months

New Medication for Early-Stage Non-small cell Lung Cancer

Already approved for advanced non-small cell lung cancer, atezolizumab is a drug that may help those with early-stage lung cancer, as well. Participants in this clinical trial may take atezolizumab in conjunction with their chemotherapy treatments.

  • Gender: Any Gender
  • Ages: 18+
  • Compensation: Not Provided
  • Time Required: The screening period may last up to 6 weeks and involve up to 2 visits to the clinic.

Lung Injury from Military Deployment

The purpose of this study is to learn more about lung disease found in contractors and U.S. military personnel serving in Iraq and Afghanistan after September 11, 2001.

  • Gender: Any Gender
  • Ages: 18-70
  • Compensation: Provided
  • Time Required: 1 to 2 visits

Link Between Rheumatoid Arthritis & Lung Disease

Our researchers are trying to understand the connection, as well as how to prevent and treat lung disease in RA patients.

  • Gender: Any Gender
  • Ages: 18+
  • Compensation: Not Provided
  • Time Required: 6 in-person visits, performed every year over 4 years

ILD & Early Rheumatoid Arthritis

Our researchers are trying to understand how interstitial lung disease (ILD) develops in people with rheumatoid arthritis (RA), and how it may impact their quality of life.

  • Gender: Any Gender
  • Ages: 18-90
  • Compensation: Not Provided
  • Time Required: 5 in-person visits over 18 months

Immune Pathways & Development of Sarcoidosis

If you are an adult with sarcoidosis who is not on immunosuppressive therapy, you may be able to help our researchers learn more about different types of sarcoidosis and how it develops.

  • Gender: Any Gender
  • Ages: 18+
  • Compensation: Provided
  • Time Required: Up to 2 visits

Mineral Dust & Lung Disease

Our researchers are studying lung diseases that develop from inhaling mineral dust over time. Although the cause of diseases such as "black lung" are known, it is not well understood why some people develop these diseases and others don't.

  • Gender: Any Gender
  • Ages: 18+
  • Compensation: Not Provided
  • Time Required: Not Specified

Investigational Medication Sirolimus for Lymphangioleiomyomatosis (LAM)

The purpose of this study is to see if a drug called sirolimus slows development of lymphangioleiomyomatosis (LAM), a lung disease in which abnormal cells growing inside the lungs prevent them from working properly.

  • Gender: Any Gender
  • Ages: 18+
  • Compensation: Provided
  • Time Required: 2 years

Can Investigational Drug Benefit Lung Cancer Surgery Patients?

The purpose of this clinical trial is to see if it better to receive an investigational medication or no further treatment after surgery (and possibly chemotherapy) to remove non-small cell lung cancer (NSCLC).

  • Gender: Any Gender
  • Ages: 18+
  • Compensation: Not Provided
  • Time Required: Up to 12 months

Pediatric Clinical Trials

SEAL Study: Stopping Eczema and Allergy

Can allergies be prevented in infants? Researchers want to know if keeping a baby’s skin healthy and hydrated with moisturizer will prevent the child from developing allergies such as food allergies. Learn how you and your child can help researchers.

  • Gender: Any Gender
  • Ages: Newborn to 10-weeks-old
  • Compensation: Provided
  • Time Required: Three years, with six clinic visits and weekly or monthly phone calls with researchers

Skin Care Impact on Skin Barrier

Infants and children up to age 18 are needed for a research study to determine if following a proper skin care routine can change the characteristics of the skin. If your child has eczema, asthma or is healthy, they may be able to help researchers with this important study.

  • Gender: Any Gender
  • Ages: 0-18
  • Compensation: Provided
  • Time Required: 1-3 clinic visits over three weeks

Skin, Airway & Esophageal Epithelial Barriers in Youth

Researchers want to better understand if the causes of asthma, eczema, food allergies, eosinophilic esophagitis and GERD can be determined at a cellular level.

  • Gender: Any Gender
  • Ages: 2-25
  • Compensation: Not Provided
  • Time Required: Up to 3 visits for a total 1 hour

Improving Asthma Treatment Using Video Chat

Can frequent video calls with a pharmacist via smart phone or computer help 14-30-year-olds take their prescribed asthma medications regularly and have fewer asthma symptoms?

  • Gender: Any Gender
  • Ages: Not Specified
  • Compensation: Provided
  • Time Required: Not Specified

SIMPLIFY Study for Cystic Fibrosis

In the SIMPLIFY study, researchers are trying to determine whether or not it is safe for people with cystic fibrosis (CF) to stop taking either inhaled hypertonic saline or Pulmozyme® (dornase alfa) if they are also taking Trikafta™.

  • Gender: Any Gender
  • Ages: 12+
  • Compensation: Provided
  • Time Required: 4 study visits, 1 phone call and daily questionnaires over 8 weeks

Systemic Allergic Reaction to SARS-CoV-2 Vaccination

Volunteers needed to determine whether highly allergic people or people with mast cell disorders are more likely to have an allergic reaction to COVID-19 vaccines than others.

  • Gender: Any Gender
  • Ages: 12+
  • Compensation: Provided
  • Time Required: 29-43 days with 2-4 clinic visits and 3-4 phone calls

SUNBEAM: Studying Allergy Development in Babies

Why do babies develop food allergies and eczema? Researchers are studying factors before birth and through age 3 that may influence the development of allergic conditions.

  • Gender: Any Gender
  • Ages: 18+
  • Compensation: Provided
  • Time Required: Up to 3 years of participation

Water Loss in the Skin of Pediatric Eczema Patients

Researchers want to know how much water is lost from the skin of pediatric patients with atopic dermatitis (eczema) before and after using the medication dupilumab.

  • Gender: Any Gender
  • Ages: 6-12
  • Compensation: Provided
  • Time Required: Up to 12 visits over 8 months

Understanding Skin Problems from Eczema and Food Allergies

Researchers are studying the differences in the skin and immune cells of people with food allergies and eczema, and those without.

  • Gender: Any Gender
  • Ages: 1-65
  • Compensation: Provided
  • Time Required: 1-2 visits, approximately 5 hours

PrecISE Severe Asthma Interventions

If you have uncontrolled asthma you may qualify for a study to help researchers understand how to treat different types of severe asthma using precision medicine.

  • Gender: Any Gender
  • Ages: 12+
  • Compensation: Provided
  • Time Required: 3 phases, approximately 9 visits per phase for up to 2 years

Investigational Treatment for Food Allergies

Our researchers are trying to determine if a study medication called omalizumab alone or combined with oral immunotherapy may help people with multiple food allergies.

  • Gender: Any Gender
  • Ages: Not Specified
  • Compensation: Provided
  • Time Required: This is a multi-stage study, with an individual study participation of up to 4 years and 8 months...

Healthy Participant Clinical Trials

Skin Care Impact on Skin Barrier

Infants and children up to age 18 are needed for a research study to determine if following a proper skin care routine can change the characteristics of the skin. If your child has eczema, asthma or is healthy, they may be able to help researchers with this important study.

  • Gender: Any Gender
  • Ages: 0-18
  • Compensation: Provided
  • Time Required: 1-3 clinic visits over three weeks

Healthy People Needed for Sarcoidosis Research

Researchers are working to understand the different ways sarcoidosis, a disease that causes scarring in the lungs, develops.

  • Gender: Any Gender
  • Ages: 18-80
  • Compensation: Provided
  • Time Required: Up to 2 visist

Water Loss in the Skin of Pediatric Eczema Patients

Researchers want to know how much water is lost from the skin of pediatric patients with atopic dermatitis (eczema) before and after using the medication dupilumab.

  • Gender: Any Gender
  • Ages: 6-12
  • Compensation: Provided
  • Time Required: Up to 12 visits over 8 months

Understanding Skin Problems from Eczema and Food Allergies

Researchers are studying the differences in the skin and immune cells of people with food allergies and eczema, and those without.

  • Gender: Any Gender
  • Ages: 1-65
  • Compensation: Provided
  • Time Required: 1-2 visits, approximately 5 hours