Scott Alper
Assistant Professor
Department of Biomedical Research
Office of Academic Affairs
Center of Genes, Environment, and Health
  • 5280 Top Doctors 2016
  • Recognized as a 5280 Top Doctor
  • America’s Top Doctors 2015 — Castle Connolly, Medical, Ltd.
  • Recognized in America’s Top Doctors — Castle Connolly, Inc.
  • Best Doctors in America® 2015 — Best Doctors, Inc.
  • Recognized in Best Doctors in America® — Best Doctors, Inc.
  • America’s Top Doctors 2016 — Castle Connolly Medical, Ltd.
  • image descriptionPrograms & Services
    Research AreasResearch Areas
    • Basic Immunology
    • Inflammation
    • Innate Immunity
    • Molecular Genetics

    Special Interests

    Diseases of the immune system such as sepsis, asthma, and atherosclerosis affect millions of people worldwide, and the incidence of many of these diseases is rising. My lab is focused on understanding the regulation of the innate immune response, particularly as it relates to the basis for such immunological diseases.

    Education

    Education
    Harvard University, PhD

    Publications

    O’Connor, BP, Danhorn, T, De Arras, L, Flatley, BR, Marcus, RA, Farias-Hesson, E, Leach, SM and Alper, S. Regulation of Toll-like receptor signaling by the SF3a mRNA splicing complex. PLOS Genetics. 11(2):e1004932 (2015).

    De Arras, L, Guthrie, BS and Alper, S. Using RNAi-interference to investigate the innate immune response in mouse macrophages. J. Vis. Exp. 93:e51306 (2014).

    De Arras, L, Laws, R, Leach, S, Pontis, K, Freedman, JH, Schwartz, DA and Alper, S. Comparative genomics RNAi screen identifies Eftud2 as a novel regulator of innate immunity. Genetics 197: 485-496 (2014).

    De Arras, L and Alper, S. Limiting of the innate immune response by SF3A-dependent control of MyD88 alternative mRNA splicing. PLOS Genetics 9(10):e1003855 (2013).

    De Arras, L, Seng, A, Lackford, B, Keikhaee, MR, Bowerman, B, Freedman, JH, Schwartz, DA, Alper, S. An evolutionarily conserved innate immunity protein interaction network. J. Biol. Chem. 288: 1967-1978 (2013).

    Academic Affiliations

    Assistant Professor in the Department of Immunology and Microbiology, University of Colorado Denver

    Website Information

    Alper Laboratory

    Contact Information

    • Office: 303.270.2659
    • Email: alpers@njhealth.org

     

    Locations

    • National Jewish Health Main Campus
      1400 Jackson St.
      Denver, CO 80206

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