James H. Finigan
Associate Professor
Department of Medicine
Division of Oncology, Cancer Center
  • 5280 Top Doctors 2016
  • Recognized as a 5280 Top Doctor
  • America’s Top Doctors 2015 — Castle Connolly, Medical, Ltd.
  • Recognized in America’s Top Doctors — Castle Connolly, Inc.
  • Best Doctors in America® 2015 — Best Doctors, Inc.
  • Recognized in Best Doctors in America® — Best Doctors, Inc.
  • America’s Top Doctors 2016 — Castle Connolly Medical, Ltd.
  • Research AreasResearch Areas
    • Cellular and Molecular Biology
    • Inflammation
    • Lung Cell Biology
    • Translational Research

    Special Interests

    Research Interests

    My research focuses on how cells of the lung adhere and how cell-cell junctions are altered during lung injury and repair. This process is relevant to numerous pulmonary diseases including acute lung injury as well as lung cancer initiation and progression.

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    University of Rochester School of Medicine, MD
    Colgate University, BA, English Literature
    University Hospitals of Cleveland, Chief Resident
    University Hospitals of Cleveland, Resident in Internal Medicine
    Johns Hopkins University School of Medicine, Pulmonary and Critical Care Fellow

    Board Certification

    2010: BLS, ACLS, Colorado License
    2008: Critical Care Medicine
    2007: Pulmonary Medicine
    2006: Medical License: Ohio
    2003: American Board of Internal Medicine

    Professional Memberships

    American Association for Cancer Research
    American Thoracic Society
    Pulmonary Circulation Assembly


    Finigan JH, Dudek SM, Singleton PA, Chiang ET, Jacobson JR, Camp SM, Ye SQ, Garcia JG. Activated protein C mediates novel lung endothelial barrier enhancement. JBC 2005;280:17286-92.

    Abdulnour RE, Peng X, Finigan JH, Han EJ, Hasan EJ, Birukov KB, Reddy SP, Watkins III JE, Kayyali US, Garcia J GN, Tuder RM, and Hassoun PM. Mechanical stress activates xanthine oxidoreductase through MAP Kinase-dependent pathways. AJP: Lung Cellular and Molecular Physiology. AJP: Lung Cellular and Molecular Physiology. 2006;291(3):345-53.

    Finigan JH. The Coagulation System and Pulmonary Endothelial Function in Acute Lung Injury. Microvascular Research. 2009; Jan;77(1):35-8.

    Finigan JH, Boueiz A, Wilkinson E, Damico R, Skirball J, Pae HH, Damarla M, Hasan E, Pearse DB, Reddy SP, Grigoryev DN, Cheadle C, Esmon CT, Garcia JG, Hassoun PM. Activated protein C protects against ventilator-induced lung injury. Am J Physiol Lung Cell Mol Physiol. 2009; 296(6):1002-11.

    Lin Z, Natesan V, Shi H, Dong F, Kawanami D, Mahabeleshwar GH, Atkins GB, Finigan JH and Jain MK. KLF2 regulates endothelial barrier function. Arterioscler Thromb Vasc Biol. 2010;30(10):1952-9.

    Hospital Affiliations

    • Colorado Acute Long Term Hospital
    • Rose Medical Center
    • St. Joseph Hospital - Denver
    • Swedish Medical Center

    Academic Affiliations

    Assistant Professor, University of Colorado, Division of Pulmonary and Critical Care Medicine

    Contact Information

    • Office: 877.225.5654



    • National Jewish Health Main Campus
      1400 Jackson St.
      Denver, CO 80206

    • Saint Joseph Hospital
      1835 Franklin Street Denver, CO 80218

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