Integrated Bioinformation and Specimen Center

The National Jewish Health Integrated Bioinformation and Specimen Center represents an ongoing institutionally-sponsored effort to collect and store the data, tissue, fluids and DNA on thousands of our patients who have generously agreed to participate in this program.

Leveraging the clinical phenotyping by our physicians, electronic research database, pathology image database and biorepository we can offer our investigators and partners highly characterized information and corresponding samples for research in the full gamut of respiratory and immunologic disease. It is our hope that this unique resource will aid in the discovery of genetic tests and biomarkers that may be useful in predicting who may get a disease, the likely course of the disease and how it may be most effectively treated.

 

Research Database

The Bioinformatics Department has developed and maintains the Research Database which allows approved researchers to view clinical data and biorepository samples in a completely de-identified way to aid in the initial formulation of a research study. Following IRB approval and a simple application to the research database advisory committee, detailed clinical data and the corresponding biologic samples will be made available to the approved investigator.

Currently archived biologic materials include:

-80ºC

• Serum 400µl or 800µl
• Plasma - EDTA 400µl or 800µl
• Plasma - Heparin 400µl or 800µl
• Buffy coat - EDTA 100µl
• Buffy coat - Heparin 100µl
• BAL - Supernatant 1.8 ml

-130ºC  

• Serum 400µl or 800µl  
• Plasma - EDTA 400µl or 800µl  
• Plasma - Heparin 400µl or 800µl  
• Buffy coat - EDTA 100µl 
• Buffy coat - Heparin 100µl 
• BAL-cells 1.8 ml
• RBCs - EDTA 1 ml
• Blood/DMSO 1 ml
• Lung tissue - Fresh Frozen (0.5-1 cm3) 

Other

• DNA, formalin-fixed tissue

 

Contacts

Steve D. Groshong, MD
Principal Investigator

George Halley
Administrator

John Yang
Research Coordinator