Center for Genes, Environment, and Health

Phone: 303-398-1903
Fax: 303-270-2136

 

The Center for Genes, Environment, and Health is dedicated to understanding the genetic basis of diseases that are common in patients cared for at National Jewish Health. The Center builds on the scientific and clinical strengths at National Jewish Health by developing programs to understand how genes work in biological systems, how genetic variants contribute to the development of disease, and why individuals with the same disease have very different results due to the treatment. These approaches will enable clinicians to develop innovative approaches to disease prevention, early diagnosis and personalized therapeutic intervention.

 

Areas of Research

• Integrated genomic technology: develop and apply novel approaches for genetic and genomic analyses, including genome sequencing, genotyping (focused and genome wide), expression microarrays, and epigenetic analyses.
• Bioinformatics and computational biology: provide support and advance the science of bioinformatics and computational analyses of complex genomic data from microorganisms to plants to humans.
• Genetic epidemiology: establish scientific programs that investigate the genetic and genomic etiology of disease in human populations.
  Comparative genomics: use complementary biological systems (such as yeast, worms, flys, zebrafish, and rodents) to discover genes that cause complex human diseases.
• Epigenetics: investigate the importance of epigenetic mechanisms (DNA methylation, histone modification, and non-coding RNA effects on gene silencing) on the development and progression of immune mediated conditions, infectious diseases, and lung diseases.
• Genomic medicine: bring the products of genomic research to the practice of personalized medicine.

Equipment and Applications

Center for Genes, Environment, and Health has the capability to run various platforms for automated DNA/RNA purification, medium throughput genotyping, gene expression, capillary DNA sequencing and next-generation sequencing. Our instruments allow flexibility and can accommodate both small and large genetics research projects.

• Automated Sample Handling and QA/QC
• Multiplex SNP Genotyping
• Microarray Applications (Including gene expression, sequence capture, DNA methylation, and CHIP-chip)
• Capillary DNA Sequencing
• Next-Generation Sequencing
• Data Storage

Learn about equipment online access at Center for Genes, Environment, and Health.

 

Faculty

David A. Schwartz, MD Director, Center for Genes, Environment, and Health Provost Smith Building A647a 303-398-1903 schwartzd@njhealth.org	Zhiyong Wang, PhD Assistant Director for Operations, Center for Genes, Environment, and Health Assistant Professor Smith Building A642 303-270-2535 wangz@njhealth.org
Ivana V. Yang, PhD Deputy Director, Center for Genes, Environment, and Health Assistant Professor Smith Building A630 303-270-2589 yangi@njhealth.org	Scott Alper, PhD Assistant Professor Smith Building A640 303-270-2659 alpers@njhealth.org
Steve Groshong, MD, PhD Assistant Director for Informatics, Center for Genes, Environment, and Health Assistant Professor Southside Building G03 303-398-1415 groshongs@njhealth.org

Contact Information
Center for Genes, Environment, and Health
c\o Linda Neese
Smith Building; A647
1400 Jackson Street
Denver, CO 80206

Phone: 303-398-1903
Fax: 303-270-2136