Gerber Lab: Publications

Abstracts available at Pub Med.

Sasse, SK and Gerber A.N. Feed-forward transcriptional programming by nuclear receptors: Regulatory principles and therapeutic implications. (Review) Pharmacology and Therapeutics, in press 2014

Altonsy O, Sasse SK, Tzu P, and Gerber A.N. Context-dependent Cooperation Between NF-kB and the Glucocorticoid Receptor at a TNFAIP3 Enhancer: A Mechanism to Maintain Negative Feedback Control of Inflammation. J Biol Chem. 2014 Mar 21;289(12):8231-9 PMID: 24500711

Sasse SK, Mailloux C, Barczak A, Wang Q, Altonsy O, Jain MK, Haldar SM and Gerber A.N. The glucocorticoid receptor and KLF15 regulate gene expression dynamics and integrate signals through feed forward circuitry. Mol Cell Biol. 2013 Jun;33(11):2104-15. PMID: 23508109

Haldar SM, Jeyaraj D, Anand P, Zhu H, Lu Y, Prosdocimo DA, Eapen B, Kawanami   D, Okutsu M, Brotto L, Fujioka H, Kerner J, Rosca MG, McGuinness OP, Snow RJ, Russell AP, Gerber AN, Bai X, Yan Z, Nosek TM, Brotto M, Hoppel CL, Jain MK. Kruppel-like factor 15 regulates skeletal muscle lipid flux and exercise adaptation. Proc Natl Acad Sci U S A. 2012 Apr 9. PMID: 22493257

Masuno K, Haldar SM, Jeyaraj D, Mailloux C, Huang X, Panettieri Jr RA, Jain MK,    Gerber A.N. 2011 Expression profiling identifies Klf15 as a glucocorticoid target that regulates Airway Hyperresponsiveness. Am J Respir Cell Mol Biol. 2011. Sep;45(3):642-9. PMID: 21257922

Gerber, A.N., Masuno K., Diamond M.I. 2009 . Discovery of selective glucocorticoid receptor modulators by multiplexed reporter screening. Proc Natl Acad Sci U S A. 2009 Mar  24;106(12):4929-34. PMID: 19255438

Gerber, A.N., Wilson C., Li, Y.J, Chuang, P.T. 2007. The Hedgehog regulated oncogenes Gli1 and Gli12 block myoblast differentiation by inhibiting MyoD-mediated transcriptional activation. Oncogene. 2007 Feb 22;26(8):1122-36 PMID: 16964293

Yun A.J., Lee P.Y., and Gerber A.N. 2006. Perspective. Integrating systems biology and medical imaging: understanding disease distribution in the lung model. Am. J. Roentgenol. April; 186(4):925-30. PMID: 16554557

Cook, D.L., Gerber, A.N., Tapscott, S.J. 1998. Modeling stochastic gene expression: Implications for haploinsufficiency. Procedings of the National Academy of Sciences, Dec 22; 26: 15641-6 PMID: 9861023

Gredinger, E., Gerber, A.N., Tamir, Y., Tapscott, S.J., Bengal, E. 1998. Mitogen-activated protein kinase pathway is involved in the differentiation of muscle cells. Journal of Biological Chemistry, Apr 24; 273: 10436-10444. PMID: 9553102

Otten. A.D., Firpo, E.J., Gerber, A.N., Brody, L.L, Roberts, J.M., Tapscott, S.J. 1997. Inactivation of MyoD mediated expression of p21 in tumor lines. Cell Growth and Differentiation, Nov 8; 11: 1151-60. PMID: 9372238

Gerber A.N., Klesert, T.R., Bergstrom, D.A., Tapscott, S.J. 1997. Two domains of MyoD mediate transcriptional activation of genes within repressive chromatin: a mechanism for lineage determination in myogenesis. Genes and Development, Feb 15; 11: 436-50. PMID:9042858

Gerber A.N. and Tapscott S.J. 1996. Tumor cell complementation groups based on myogenic potential: evidence for inactivation of loci required for basic helix-loop-helix protein activity. Molecular and Cellular Biology, Jul 16; 7: 3901-8. PMID: 8668208

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