Leach Lab: Publications

Online bibliography

O'Connor BP, Danhorn T, De Arras L, Marcus RA, Farias-Hesson E, Leach SM, Alper S. Regulation of Toll-like receptor signaling by the SF3a mRNA splicing complex. PLoS Genetics 2014. 2015; 11(2):e1004932.

Kim J, Vasu VT, Mishra R, Singleton KR, Yoo M, Leach SM, Farias-Hesson E, Mason RJ, Kang J, Ramamoorthy P, Kern JA, Heasley LE, Finigan JH, Tan AC. Bioinformatics-driven discovery of rational combination for overcoming EGFR-mutant lung cancer resistance to EGFR therapy. Bioinformatics 2014. May 7.

De Arras L, Laws R, Leach SM, Pontis K, Freedman JH, Schwartz DA, Alper S (2013) Comparative Genomics RNAi Screen Identifies Eftud2 as a Novel Regulator of Innate Immunity. Genetics. 2013 Dec 20.

Gabehart K, Correll KA, Yang J, Collins ML, Loader JE, Leach S, White CW, Dakhama A (2013) Transcriptome profiling of the newborn mouse lung response to acute ozone exposure. Toxicol Sci. 2013 Dec 12.

Yang IV, Coldren CD, Leach SM, Seibold MA, Murphy E, Lin J, Rosen R, Neidermyer AJ, McKean DF, Groshong SD, Cool C, Cosgrove GP, Lynch DA, Brown KK, Schwarz MI, Fingerlin TE, Schwartz DA. (2013) Expression of cilium-associated genes defines novel molecular subtypes of idiopathic pulmonary fibrosis. Thorax. 2013 Jun 19.

Yang IV, Luna LG, Cotter J, Talbert J, Leach SM, et al. (2012) The Peripheral Blood Transcriptome Identifies the Presence and Extent of Disease in Idiopathic Pulmonary Fibrosis. PLoS ONE 7(6): e37708.

Bin L, Kim BE, Hall CF, Leach SM, Leung DYM, "Inhibition of Transcription Factor Specificity Protein 1 Alters the Gene Expression of Keratinocytes Leading to Up-regulation of Kallikrein-related Peptidases and TSLP", Journal of Investigative Dermatology, 2011. Abstract

Yu S, Tranchevent L, Leach SM, De Moor B, Moreau Y. A kernel based framework for cross-species candidate gene prioritization, Machine Learning in Systems Biology, 2011.

Feng W, Leach SM, Tipney H, Phang T, Geraci M, Spritz R, Hunter L, Williams T. Spatial and Temporal Analysis of Gene Expression During Growth and Fusion of the Mouse Facial Prominences. PLoS ONE. 2009; 4(12): e8066. Abstract

Leach SM, Tipney H, Feng W, Baumgartner WA, Kasliwal P, Schuyler RP, Williams T, Spritz RA, Hunter L. Biomedical Discovery Acceleration, with Applications to Craniofacial Development. PLoS Comput Bio, 2009, 5(3):e1000215. Abstract

Tipney HJ, Leach SM, Feng W, Spritz R, Williams T, Hunter L. Leveraging existing biological knowledge in the identification of candidate genes for facial dysmorphology. AMIA Summit on Translational Bioinformatics BMC Bioinformatics Special Issue, 2009, 10(Suppl2):S12. Abstract

Karimpour-Fard A, Leach SM, Gill RT, Hunter LE. Predicting protein linkages in bacteria: which method is best depends on task. BMC Bioinformatics. 2008 Sep 24;9:397. Abstract

Karimpour-Fard A, Leach SM, Hunter LE, Gill RT. The topology of the bacterial co-conserved protein network and its implications for predicting protein function. BMC Genomics. 2008 Jun 30;9:313. Abstract

Gabow AP, Leach SM, Baumgartner WA, Hunter LE, Goldberg DS. Improving protein function prediction methods with integrated literature data. BMC Bioinformatics. 2008 Apr 15;9:198. Abstract

Bhave SV, Hornbaker C, Phang TL, Saba L, Lapadat R, Kechris K, Gaydos J, McGoldrick D, Dolbey A, Leach S, Soriano B, Ellington A, Ellington E, Jones K, Mangion J, Belknap JK, Williams RW, Hunter LE, Hoffman PL, Tabakoff B. The PhenoGen Informatics website: tools for analyses of complex traits. BMC Genetics. 2007; 8:59. Abstract

Leach SM, Gabow A, Hunter L, Goldberg DS. Assessing and Combining Reliability of Protein Interaction Sources. Pacific Symposium of Biocomputing. 2007; 12:433444. Abstract

Lowes BD, Zolty R, Minobe WA, Robertson AD, Leach S, Hunter L, Bristow MR. Serial gene expression profiling in the intact human heart. Journal of Heart and Lung Transplant. 2006; 25(5):57988. Abstract

Acquaah-Mensah GK, Leach SM, Guda C. Predicting the subcellular localization of human proteins using machine learning and exploratory data analysis. Genomics Proteomics Bioinformatics. 2006; 4(2):12033. Abstract