Research Areas
- Cellular and Molecular Biology
- Computational Biology
- Genomics
- Infectious Diseases
- Mycobacterial and Respiratory Infections
- Structural Biology
- Translational Research
- Tuberculosis
- Gender:
- Male
Education & Training
Education
- 2005
- University of California, Los Angeles, PhD
Fellowship
- 2006-2010
- Harvard Medical School, Postdoctoral Fellow
Special Interests
Research Interests
Dr. Strong’s research focuses on synergistic genomic, computational and molecular strategies to disease and disease pathogenesis. I am particularly interested in developing and applying computational methods to better generate, integrate and analyze genomic and proteomic information, with a focus on respiratory disease and disease pathogens, including Mycobacterium tuberculosis. Some of Dr. Strong’s current collaborative projects include complete genome sequencing, gene expression analysis, protein and gene network analysis, and structural informatics. It is Dr. Strong’s hope that these strategies will help elucidate the underlying mechanisms of disease and suggest new ways to combat, prevent and limit disease and drug resistance.
Teaching or Professional Positions
University of Colorado Denver, Bioinformatics I, CPBS 7711
University of Colorado Denver, Bioinformatics II, CPBS 7712
Professional Memberships
University of Colorado, Center for Global Health, Affiliate
International Society for Computational Biology, Member
Awards & Recognition
Jane Coffin Childs Memorial Fund For Medical Research, Postdoctoral Fellowship, Harvard Medical School
National Institutes of Health, National Research Service Award (Cell and Molecular Biology Training Grant, UCLA)
Paul D. Boyer Outstanding Teaching Award
Publications
Sandgren A, Strong M, Mutukrishnan P, Weiner BK, Church GM, Murray MB. Tuberculosis Drug Resistance Mutation Database PLoS Medicine 2009; 6:2. PMID: 19209951
Strong M, Eisenberg D. The Protein Network as a Tool for Finding Novel Drug Targets. Progress in Drug Research 2007; 64:193-215. PMID: 17195476
Strong M, Sawaya M, Wang S, Philips M, Cascio D, Eisenberg D. Toward the Structural Genomics of Complexes: Crystal Structure of a PE/PPE protein complex from Mycobacterium tuberculosis. Proc. Natl. Acad. Sci. U. S. A. 2006; 103:8060-8065. PMID: 16690741
Strong M, Graeber TG, Beeby M, Pellegrini M, Thompson MJ, Yeates TO, Eisenberg D. Visualization and Interpretation of Protein Networks in Mycobacterium tuberculosis Based on Hierarchical Clustering of Genome-Wide Functional Linkage Maps. Nucleic Acids Research 2003; 31: 7099-7109. PMID: 14654685
Strong M, Mallick P, Pellegrini M, Thompson MJ, Eisenberg D. Inference of Protein Function and Protein Linkages in M. tuberculosis Based on Prokaryotic Genome Organization: A Combined Computational Approach. Genome Biology 2003; 4:R59.1-R59.16. PMID: 12952538