It is important to recognize that there is no cure for Sjögren's. In addition, because it is a chronic disease, people often require medical therapy for many years.
Goals of therapy vary for each person as treatment is guided by the organs that are affected. Artificial tears and ointments are used to keep the eyes moist. On occasion, ophthalmologic procedures are needed to maintain eye moisture.
Artificial saliva tablets and some saliva-stimulants (pilocarpine/Salagen and cevimeline/Evoxac) are used for dryness of the mouth. People with Sjögren's require frequent dental check-ups to help maintain oral hygiene.
When there is evidence of blood vessel damage, nervous system or lung involvement due to Sjögren's, potent immunosuppression with corticosteroids (such as prednisone) and other immunosuppressants may be required. This is used to control the underlying autoimmune and inflammatory response.