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Azzeddine Dakhama

Azzeddine Dakhama, PhD

  • Associate Professor
  • Department of Pediatrics

Profile

Research Areas

  • Allergy
  • Asthma
  • Infectious Diseases
  • Inflammation
Gender:
Male

Education & Training

Education

1980
University of Rabat (Morocco), BS, Biology
1983
University of Lille (France), MS, Biology
1991
Laval University (Quebec, Canada), PhD, Biology

Fellowship

1992-1993
Laval University, Laval Hospital, Pulmonary Research Center (Quebec, Canada), Asthma, Hypersensitivity Pneumonitis, Lung Inflammation
1993-1996
University of British Columbia, St. Paul’s Hospital, Pulmonary Research Laboratory (Vancouver, Canada), Asthma, Respiratory Viral Infections, Lung Pathology

Special Interests

Research Interests

My research is focused on the mechanisms that determine the outcome of early age exposure to respiratory viral infection and allergen exposure. I am particularly interested in defining how maternal immunity and other factors (e.g. environmental pollution) influence the early host response to respiratory viruses and allergens in the postnatal development period.

Affiliations with the University of Colorado Denver

Associate Professor, Department of Pediatrics

Professional Memberships

American Thoracic Society (ATS)
American Academy of Allergy Asthma and Immunology (AAAAI)

Publications

Dakhama A, Lee YM, Ohnishi H, Jing X, Balhorn A, Takeda K, Gelfand EW. Virus-specific IgE enhances airway responsiveness on reinfection with respiratory syncytial virus in newborn mice. J Allergy Clin Immunol 2009; 123: 138-145.

Lee YM, Miyahara N, Takeda K, Prpich J, Oh A, Balhorn A, Joetham A, Gelfand EW, Dakhama A. IFN-gamma production during initial infection determines the outcome of reinfection with respiratory syncytial virus. Am J Respir Crit Care Med. 2008; 177(2):208-218.

Dakhama A, Park JW, Taube C, Joetham A, Balhorn A, Miyahara N, Takeda K, Gelfand EW. The enhancement or prevention of airway hyperresponsiveness during reinfection with respiratory syncytial virus is critically dependent on the age at first infection and IL-13 production. J Immunol. 2005; 175:1876-1883.

Dakhama A, Park JW, Taube C, El Gazzar M, Kodama T, Miyahara N, Takeda K, Kanehiro A, Balhorn A, Joetham A, Loader JE, Larsen GL, Gelfand EW. Alteration of airway neuropeptide expression and development of airway hyperresponsiveness following respiratory syncytial virus infection. Am J Physiol Lung Cell Mol Physiol. 2005; 288:L761-770.

Dakhama A, Park JW, Taube C, Chayama K, Balhorn A, Joetham A, Wei XD, Fan RH, Swasey C, Miyahara N, Kodama T, Alvarez A, Takeda K, Gelfand EW. The role of virus-specific immunoglobulin E in airway hyperresponsiveness. Am J Respir Crit Care Med. 2004; 170:952-9.

More Publications by This Author

Link to Faculty Publications

Link to PubMed for more papers

Office Information

Doctor's Contact Information

  • Office: 303.398.1705

Locations

  • Main Campus
    1400 Jackson St.
    Denver, CO 80206
    Main: 877.225.5654