Roland M du Bois
MD
- Phone
- 303-398-1867
- Fax
- 303-398-1452
- Email
- duBoisR@njhealth.org
- Gender
- Male
Specialties
Research
Autoimmunity/Rheumatology, Cellular and Molecular Biology, Environmental and Occupational Diseases, Genetics, Inflammation, Interstitial Lung Disease(ILD)/Pulmonary Fibrosis
Professional Memberships/Societies
2003-Present: American College of Chest Physicians
1991-Present: European Respiratory Society
1983-Present: American Thoracic Society
1981-Present: British Thoracic Society
Board Certified
1988: Fellow of the Royal College of Physicians, UK
1982: Accreditation in General (Internal) Medicine and Respiratory Medicine
1981: MD Cambridge, UK
Research Interests
I am involved in: the setting up of a rheumatological lung disease program that will define the clinical and molecular phenotypes of lung disease that occurs in the context of rheumatological disease; developing a programme of research into hypersensitivity pneumonitis across the divisions of pulmonary medicine and DEOHS; working with David Schwartz on the development of the Center for Genetics and Therapeutics; and studies into the genetic background to fibrosing and granulomatous lung disease. In each of these endeavors, a common goal is to bridge basic and clinical science into a bonded multidisciplinary translational research program with the patient at the core.
Education & Training
Education
- University of Cambridge, UK
- 1966-1972
Residencies
- Royal Free Hospital, London
- General Internal Medicine, 1979-1981
- Royal London Hospital, London
- General Internal Medicine and Pulmonary, 1975-1977
Fellowships
- Royal Brompton Hospital, London
- Pulmonary, 1981
- Royal Brompton Hospital, London
- Pulmonary, 1977-1979
Awards & Recognition
Honors/Awards
1999-2008: Professor of Respiratory Medicine, National Heart & Lung Institute, Imperial College
1999-2008: Visiting Professor, National Jewish
March 2006: Visiting Professor, Royal Melbourne Hospital, Australia
1999-2006: Several European Respiratory Society awards for European fellows to study in my lab
1998: Scholarship from Kyoto University to visit Chest Diseases Research Institute to develop collaborative projects
1987-89: Fulbright Scholar
Editorial Boards
2007: Assoc Editor, Clinical Respiratory Journal (Nordic)
2007: Editorial Board, The Open Respiratory Medicine Journal
2006: Editorial Board, Expert Review of Respiratory Medicine
2006: Editorial Board, CHEST
2005: Assoc Editor, Monaldi Archives for Chest diseases
2001-05: Assoc Editor, Am. Journal of Respiratory & Critical Care Medicine
2000-04: Editorial Board Respiratory Research
2000-03: Assoc Editor, Respiratory Research
1999: Editorial Board Current Opinion in Pulmonary Medicine
1999: Editorial Board, Seminars in Respiratory and Critical Care Medicine
1994-96: Assoc Editor, Thorax
1995: Member Editorial Board Sarcoidosis Vasculitis and Interstitial Lung Diseases
1985–87: Assoc Editor Thorax
1984-87: Member Editorial Board Thorax
Recent or Important Publications
Spagnolo P, Sato H, Grunewald J, Brynedal B, Hillert J, Mañá J, Wells AU, Eklund A, Welsh KI, du Bois RM A common haplotype of the C-C chemokine receptor 2 gene and HLA-DRB1*0301 are independent genetic risk factors for Löfgren's syndrome. J Intern Med. 2008 May 29. [Epub ahead of print]
William D. Travis, Gary Hunninghake, Talmadge E King, Jr., David A. Lynch, Thomas V. Colby, Jeffrey R. Galvin, Kevin K. Brown, Man Pyo Chung, Jean-Francois Cordier, Roland M. Dubois, Kevin R. Flaherty,Teri J. Franks, David M. Hansell, Thomas E. Hartman, Ella A. Kazerooni, Dong Soon Kim, Masanori Kitaichi, Takashi Koyama, Fernando J. Martinez, Sonoko Nagai, David E. Midthun, Nestor L. Müller, Andrew G. Nicholson, Ganesh Raghu, Moises Selman, Athol Wells. Idiopathic Nonspecific Interstitial Pneumonia: Report of an ATS Project. AJRCCM Articles In Press. Published On April 3, 2008.
Fonseca C, Lindahl GE, Ponticos M, Sestini P, Renzoni EA, Holmes AM, Spagnolo P, Pantelidis P, Leoni P, McHugh N, Stock CJ, Shi-Wen X, Denton CP, Black CM, Welsh KI, du Bois RM, Abraham DJ. A polymorphism in the CTGF promoter region associated with systemic sclerosis. N Engl J Med. 2007 Sep 20;357(12):1210-20.
Spagnolo P, Sato H, Grutters JC, Renzoni EA, Marshall SE, Ruven HJ, Wells AU, Tzouvelekis A, van Moorsel CH, van den Bosch JM, du Bois RM, Welsh KI. Analysis of BTNL2 genetic polymorphisms in British and Dutch patients with sarcoidosis. Tissue Antigens. 2007 Sep;70(3):219-27.
Hoyles RK, Ellis RW, Wellsbury J, Lees B, Newlands P, Goh NS, Roberts C, Desai S, Herrick AL, McHugh NJ, Foley NM, Pearson SB, Emery P, Veale DJ, Denton CP, Wells AU, Black CM, du Bois RM. A multicenter, prospective, randomized, double-blind, placebo-controlled trial of corticosteroids and intravenous cyclophosphamide followed by oral azathioprine for
the treatment of pulmonary fibrosis in scleroderma. Arthritis Rheum. 2006 Dec;54(12):3962-70.