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Rafeul Alam
MD, PhD
- Department of Medicine
- Head, Division of Allergy & Clinical Immunology
- Veda H. and Chauncey H. Ritter Chair in Immunology
- Professor
- Gender
- Male
Specialties
Adults
Allergic and Immunologic Conditions
Allergic Bronchopulmonary Aspergillosis, Anaphylaxis, Angioedema, Atopic Dermatitis (Eczema), Drug Allergy, Eosinophilic Disorders, Food Allergy, Hay Fever/Rhinitis (Allergic & Non-allergic), Immune Deficiencies, Insect Sting Allergy, Mastocytosis, Occupational Allergy, Sinusitis, Urticaria/Hives
Asthma
Exercise-Induced Asthma, Occupational Asthma
Pulmonary/Lung Conditions
Chronic Cough
Research
Allergy, Asthma, Basic Immunology, Cellular and Molecular Biology, Inflammation
Affiliation with University of Colorado Denver
University of Colorado Denver - Program B Fellowship Program
Professional Memberships/Societies
1997-Present: American Society for Clinical Investigation
1993-Present: Southern Society for Clinical Investigation
1992-Present: American College of Physicians
1990-Present: Greater Houston Allergy Society
1990-Present: Texas Allergy Society
1990-Present: Texas Medical Association
1990-Present: Galveston County Medical Society
1989-Present: American Thoracic Society
1989-Present: American Association of Immunologists
1988-Present: American Academy of Allergy and Immunology
1986-Present: Sigma Xi
1986-Present: American College of Allergists
Publications by This Author
Link to Faculty Publications
Board Certified
American Board of Internal Medicine
American Board of Allergy and Immunology
Research Interests
1. Basic Science Research: The major research interest of the laboratory is signal transduction mechanism of eosinophils and T cells, and signaling mechanism of asthma.
2. Translational/Clinical Research: The major interests are the signaling abnormalities of asthma and airway allergic diseases.
Service
Education & Training
Education
- Lodz Medical School (Lodz, Poland)
- MD, 1974-1980
Residencies
- Lodz Medical School (Lodz, Poland)
- Internal Medicine, 1981-1983
- Lodz Medical School (Lodz, Poland)
- Internal Medicine, 1980-1981
Fellowships
- University of Texas Medical Branch at Galveston
- Allergy-Immunology, 1987-1988
- University of Texas Medical Branch at Galveston
- Allergy-Immunology, 1986-1987
Awards & Recognition
Veda and Chauncey Ritter Chair in Immunology, National Jewish Health
Elected member, American Society for Clinical Investigation
AITR Study Section Member, 2000-2004
Ad hoc Study Section Member: ALY, IMS
Recent or Important Publications
Liu W, Liang Q, Balzar S, Wenzel S, Gorska MM, and Alam R. Cell-specific Activation of ERK1/2, JNK and p38 Kinases in the Airway Tissue from Asthmatic Patients. J. Allergy Clin. Immunol. 121(4): 893-902.e2, 2008.
Goplen N, Gorska MM, Stafford SJ, Rosario S, Lei G, Liang Q, and Alam R. A Phospho-site Screen Identifies Autocrine TGF beta driven Activation of Protein Kinase R as a Survival-limiting Factor For Eosinophils. J. Immunol. 180(6): 4256-64, 2008.
Gorska MM, Stafford SJ, Liang Q, Dharajiya N, Guo L, Sur S, Gaestel M, and Alam R. MK2 controls the level of positive feedback in the NFkB pathway and is essential for endothelial permeability and airway inflammation. J. Exp. Med. 204 1637-1652, 2007.
Vepachedu R, Gorska M, Singhania N, Cosgrove G, Brown K, and Alam R. Unc119 Regulates Myofibroblast Transformation Through the Activation of Fyn and p38 MAPK Pathway. J. Immunol. 179: 682-690, 2007.
Gorska MM, Stafford S, Cen O, Sur S, Alam R. Unc119, a novel Src kinase activator is essential for T cell receptor signal generation. J. Exp. Med. 199: 369-379, 2004.
