Remy Kachadourian
PhD
- Department of Medicine
- Instructor
- Gender
- Male
Specialties
Research
Cancer, Environmental and Occupational Diseases, Oxidative Stress
Teaching & Professional Positions
2000-2007: Research Associate (post-doc) at National Jewish Health (Denver, CO, USA), Pro- and anti-oxidant properties of natural compounds (estrogens and flavonoids). Structure/antioxidant activity of new manganese-porphyrins. Mentor: Prof. Brian J. Day.
1997-1999: Research Associate (post-doc) at Duke University Medical Center (Durham, NC, USA), Synthesis and superoxide dismutase activity of new manganese-porphyrins, Mentor: Prof. I. Fridovich.
Professional Memberships/Societies
2007-Present: Reviewer for the Journal of Mass Spectrometry
2005-Present: Reviewer for the Journal of Inorganic Biochemistry
2000-Present: Member of the Society of Free Radical in Biology and Medicine
Publications by This Author
Link to Faculty Publications
Link to PubMed for more papers
Education & Training
Education
- Université de Paris-Sud (Orsay, France)
- PhD, Biological Chemistry, 1992-1996
- Université de Paris-Sud (Orsay, France)
- MS, Bioinorganic Chemistry, 1992
- Université de Paris-Sud (Orsay, France)
- BS, Biochemistry, 1991
Recent or Important Publications
Leitner HM, Kachadourian R, Day BJ. Harnessing drug resistance: using ABC transporter proteins to target cancer cells. Biochemical Pharmacology 74:1677-1685, 2007.
Kachadourian R, Leitner HM, Day BJ. Selected flavonoids potentiate the toxicity of cisplatin in human lung adenocarcinoma cells: a role for glutathione depletion. International Journal of Oncology 31:161-168, 2007.
Velsor LW, Kariya C, Kachadourian R, Day BJ. Mitochondrial oxidative stress in the lungs of cystic fibrosis trans-membrane conductance regulator protein mutant mice. Respiratory Cell and Molecular Biology 35:579-586, 2006.
Kachadourian R, Day BJ. Flavonoid-induced glutathione depletion: potential implications for cancer treatment. Free Radical Biology and Medicine 41:65-76, 2006.
Kachadourian R, Johnson CA, Min E, Spasojevic I, Crapo JD, Day BJ. Flavin-dependent antioxidant properties of a new series of meso-N,N'-dialkyl-imidazolium substituted manganese(III) porphyrins. Biochemical Pharmacology 67:77-85, 2004.
