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Brian J Day
PhD
- Department of Medicine
- Integrated Department of Immunology
- Professor
- Phone
- 303-398-1121
- Email
- dayb@njhealth.org
- Gender
- Male
Specialties
Research
Basic Immunology, COPD/Chronic Obstructive Pulmonary Disease/Emphysema, Cystic Fibrosis, Chronic Beryllium Disease, Environmental and Occupational Diseases, Infectious Diseases, Inflammation, Lung Cancer, Oxidative Stress
Affiliation with University of Colorado Denver
Associate Professor of Medicine, Pulmonary Division
Associate Professor of Pharmaceutical Sciences
Professional Memberships/Societies
Society of Toxicology
American Thoracic Society
Society of Free Radical Biology and Medicine
American Heart Association
American Chemical Society
Publications by This Author
Link to Faculty Publications
Research Interests
Cystic Fibrosis, COPD, chronic beryllium disease, interstitial lung disease, sulfur mustard lung injury, drug development.
Adaptive glutathione responses to cigarette smoke in COPD. (NIH RO1 HL084469) (Primary Investigator).
Efficacy of Metalloporphyrins in Ulcerative Colitis. Aeolus Pharmaceuticals Grant (Primary Investigator).
Development of Novel Therapies to Treat Chronic Lung Disease. Colorado Bioscience Discovery Grant (Primary Investigator).
Novel Antioxidant Therapeutics for Sulfur Mustard Toxicity. (NIH U54 ES015678-01) (Project 2 Leader).
Education & Training
Education
- Purdue University (W Lafayette, IN)
- PhD, Pharmacology and Toxicology, 1992
- University of Montana (Missoula, MT)
- BS with Honors, School of Pharmacy, 1984
Fellowships
- Duke University (Durham, NC)
- Post-doctoral Integrated Toxicology & Pulmonary Fellow, 1995
Awards & Recognition
Basic Sciences Section Head, Department of Medicine, National Jewish Health
Chief Science Officer, Aeolus Pharmaceuticals
Chairman, Board of Publications Committee, Mechanisms Specialty Section Councilor, Society of Toxicology
NIH Study Section Member, LIRR
Recent or Important Publications
Dobis, D.R., Sawyer R.T., Gillespie M.M., Huang J., Newman L.S., Maier L.A. and Day B.J. Modulation of Lymphocyte Proliferation by Antioxidants in Chronic Beryllium Disease. Am. J. Respir. Crit. Care Med. 177:1002-1011, 2008.
Day, B.J. Antioxidants as potential therapeutics for lung fibrosis. Antiox Redox Sig,10:355-370, 2008.
Kachadourian, R and Day, B.J. Flavonoid-induced glutathione depletion: potential implications for cancer treatment. Free Radic. Biol. Med. 41:65-76, 2006.
Velsor, L.W., Kariya C., Kachadourian, R., and Day, B.J. Mitochondrial oxidative stress in the lungs of cystic fibrosis transmembrane conductance regulator protein mutant mice. Am. J. Respir. Cell Mol. Biol. 35:579-586, 2006.
Day BJ, van Heeckeren AM, Min E, and Velsor L. Role for CFTR in a glutathione response to bronchopulmonary pseudomonas infection. Infect Immun 72:2045-2051, 2004.
