Kathryn Haskins
PhD
- Integrated Department of Immunology
- Phone
- 303-270-2093
- Fax
- 303-270-2325
- Email
- katie.haskins@uchsc.edu
- Gender
- Female
Specialties
Research
Basic Immunology, Type-1 Diabetes
Affiliation with University of Colorado Denver
Professor, Department of Immunology
Professional Memberships/Societies
AAI, American Diabetes Association
Publications by This Author
Link to Faculty Publications
Research Interests
T cell immunology, autoimmunity, type 1 diabetes.
Our research is to investigate the mechanisms and regulation of pathogenesis in the NOD mouse model of type 1 diabetes. We used cloned T cell lines and TCR transgenic mice to study the disease process. We are also interested in the beta cell autoantigens that activate autoreactive T cells in type 1 diabetes.
Education & Training
Education
- University of Kansas (Lawrence, KS)
- PhD, Biochemistry, 1981
Fellowships
- National Jewish Health
- Postdoctoral Fellowship in Immunology, 1981-1986
Recent or Important Publications
Haskins, K. 2005. Pathogenic T cell clones in autoimmune diabetes: more lessons from the NOD mouse. Advances in Immunol. 87: 123-62.
Pauza, M. E., Dobbs, C. M., He, J., Patterson, T., Wagner, S., Anobile, B., Bradley, B., Lo, D. and Haskins, K. 2004. TCR transgenic response to an endogenous polymorphic autoantigen determines susceptibility to diabetes. Diabetes 53: :978-988.
Haskins, K., Kench, J., Powers, K., Bradley, B., Pugazhenthi, S., Reusch, J. and McDuffie, M. 2004. Role for oxidative stress in the regeneration of islet beta cells? J. Invest. Med. 52: 45-49.
Stratmann, T., Martin-Orozco, N., Mallet-Designe, V., Poirot, L., McGavern, D., Losyev, G., Dobbs, C.M., Oldstone, M.B.A., Yoshida, K., Kikutani, H., Mathis, D., Benoist, C., Haskins, K. and Teyton, L. 2003. Susceptible MHC alleles, not background genes, select an autoimmune T cell reactivity. J. Clin. Invest. 112: 902-14.
Wagner, D.H., Vaitaitis, G., Sanderson, R., Poulin , M., Dobbs, C. and Haskins, K. (2002) Expression of CD40 identifies a unique pathogenic T cell population in type 1 diabetes. PNAS 99: 3782.
